InnateDB Protein
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IDBP-79965.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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LANCL1
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Protein Name
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LanC lantibiotic synthetase component C-like 1 (bacterial)
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Synonyms
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GPR69A; p40;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000233714
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InnateDB Gene
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IDBG-79963 (LANCL1)
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Protein Structure
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Function |
May play a role in EPS8 signaling. Binds glutathione. {ECO:0000269PubMed:19528316}.
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Subcellular Localization |
Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Note=Detected at the surface of Maurer's clefts in malaria-infected erythrocytes at late stages of parasite development.
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Disease Associations |
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Tissue Specificity |
Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis. {ECO:0000269PubMed:10944443, ECO:0000269PubMed:15811525, ECO:0000269PubMed:9512664}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
11
[view]
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Protein-Protein |
9
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007822
Lanthionine synthetase C-like
IPR008928
Six-hairpin glycosidase-like
IPR020464
LanC-like protein, eukaryotic
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PFAM |
PF05147
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PRINTS |
PR01950
PR01951
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O43813
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PhosphoSite |
PhosphoSite-O43813
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TrEMBL |
Q53TN2
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UniProt Splice Variant |
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Entrez Gene |
10314
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UniGene |
Hs.712663
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RefSeq |
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HUGO |
HGNC:6508
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OMIM |
604155
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CCDS |
CCDS2392
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HPRD |
16040
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IMGT |
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EMBL |
AC007970
AJ289236
AJ289237
AJ289238
AJ289239
BC028685
CH471063
Y11395
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GenPept |
AAH28685
AAY14696
CAA72205
CAC21950
EAW70487
EAW70488
EAW70489
EAW70490
EAW70491
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