Version 5.4
Homo sapiens Protein: IKZF2
Summary
InnateDB Protein IDBP-80034.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IKZF2
Protein Name IKAROS family zinc finger 2 (Helios)
Synonyms ANF1A2; HELIOS; ZNF1A2; ZNFN1A2;
Species Homo sapiens
Ensembl Protein ENSP00000363439
InnateDB Gene IDBG-80024 (IKZF2)
Protein Structure
UniProt Annotation
Function Associates with Ikaros at centromeric heterochromatin.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKS7
PhosphoSite PhosphoSite-Q9UKS7
TrEMBL Q53RV5
UniProt Splice Variant
Entrez Gene 22807
UniGene Hs.618886
RefSeq NP_001072994
HUGO HGNC:13177
OMIM 606234
CCDS CCDS46507
HPRD 05872
IMGT
EMBL AC013736 AC079610 AC108066 AF130863 AY587062 AY587064 AY587065 AY587066 AY587067 AY587068 AY587069 AY587070 AY587071 AY587072 BC028936 CH471063
GenPept AAF09441 AAH28936 AAS99855 AAS99857 AAS99858 AAS99859 AAS99860 AAS99861 AAS99862 AAS99863 AAS99864 AAS99865 AAX93263 AAY24327 EAW70508 EAW70513

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca