InnateDB Protein
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IDBP-80318.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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AKAP2
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Protein Name
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A kinase (PRKA) anchor protein 2
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Synonyms
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AKAP-2; AKAPKL; PRKA2;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000259318
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InnateDB Gene
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IDBG-405943 (AKAP2)
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Protein Structure
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Function |
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
12
[view]
|
Protein-Protein |
11
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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PDB ID |
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InterPro |
IPR018459
RII binding domain
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PFAM |
PF10522
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y2D5
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PhosphoSite |
PhosphoSite-Q9Y2D5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
445815
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UniGene |
Hs.733138
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RefSeq |
NP_001130034
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HUGO |
HGNC:372
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OMIM |
604582
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CCDS |
CCDS48003
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HPRD |
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IMGT |
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EMBL |
AB023137
AJ303079
AK057098
AK300427
AL110268
AL158823
AL158829
AL353598
AL353806
AL627225
BC140818
BC146863
BC171800
CH471105
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GenPept |
AAI40819
AAI46864
AAI71800
BAA76764
BAG51862
BAG62154
CAB53707
CAC38839
CAI10811
CAI12434
CAI13896
CAI39560
CAI40816
EAW59057
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