Version 5.4
Homo sapiens Protein: AKAP2
Summary
InnateDB Protein IDBP-80320.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKAP2
Protein Name A kinase (PRKA) anchor protein 2
Synonyms AKAP-2; AKAPKL; PRKA2;
Species Homo sapiens
Ensembl Protein ENSP00000363649
InnateDB Gene IDBG-405943 (AKAP2)
Protein Structure
UniProt Annotation
Function Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Protein Structure and Domains
PDB ID
InterPro IPR018459 RII binding domain
PFAM PF10522
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y2D5
PhosphoSite PhosphoSite-Q9Y2D5
TrEMBL
UniProt Splice Variant
Entrez Gene 445815
UniGene Hs.733138
RefSeq NP_001004065
HUGO HGNC:372
OMIM 604582
CCDS CCDS43861
HPRD
IMGT
EMBL AB023137 AJ303079 AK057098 AK300427 AL110268 AL158823 AL158829 AL353598 AL353806 AL627225 BC140818 BC146863 BC171800 CH471105
GenPept AAI40819 AAI46864 AAI71800 BAA76764 BAG51862 BAG62154 CAB53707 CAC38839 CAI10811 CAI12434 CAI13896 CAI39560 CAI40816 EAW59057

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca