InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: USP42

Summary

InnateDB Protein

IDBP-8044.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USP42

Protein Name

ubiquitin specific peptidase 42

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000301962

InnateDB Gene

IDBG-8042 (USP42)

Protein Structure

UniProt Annotation

Function

Deubiquitinating enzyme which may play an important role during spermatogenesis. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Broadly expressed. {ECO:0000269PubMed:14715245}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.

Experimentally validated
Total	34 [view]
Protein-Protein	34 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004843	ubiquitin-specific protease activity
GO:0005515	protein binding
GO:0036459	ubiquitinyl hydrolase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007283	spermatogenesis
GO:0016579	protein deubiquitination
GO:0030154	cell differentiation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain

PFAM

PF00443

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9H9J4

PhosphoSite

PhosphoSite-Q9H9J4

TrEMBL

E5RJP3

UniProt Splice Variant

Entrez Gene

84132

UniGene

Hs.707731

RefSeq

NP_115548

HUGO

HGNC:20068

OMIM

CCDS

CCDS47535

HPRD

IMGT

EMBL

AC004895 AJ601395 AK022759 AY618868 BC060846 BC132862

GenPept

AAH60846 AAI32863 AAT67238 BAB14232 CAE53097