Version 5.4
Homo sapiens Protein: POU5F1
Summary
InnateDB Protein IDBP-806648.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POU5F1
Protein Name POU class 5 homeobox 1
Synonyms Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4;
Species Homo sapiens
Ensembl Protein ENSP00000484778
InnateDB Gene IDBG-77210 (POU5F1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 315 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 40 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 315 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000327 POU-specific
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR010982 Lambda repressor-like, DNA-binding domain
IPR013847 POU domain
PFAM PF00157
PF00046
PF13413
PRINTS PR00028
PIRSF
SMART SM00352
SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL U3KQH6
UniProt Splice Variant
Entrez Gene 5460
UniGene
RefSeq NP_976034
HUGO HGNC:9221
OMIM 164177
CCDS CCDS47398
HPRD
IMGT
EMBL AL662844
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca