InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CRY2

Summary

InnateDB Protein

IDBP-806790.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CRY2

Protein Name

cryptochrome circadian clock 2

Synonyms

HCRY2; PHLL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000478187

InnateDB Gene

IDBG-41167 (CRY2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0000989	transcription factor binding transcription factor activity
GO:0003677	DNA binding
GO:0003684	damaged DNA binding
GO:0003697	single-stranded DNA binding
GO:0003913	DNA photolyase activity
GO:0005515	protein binding
GO:0009882	blue light photoreceptor activity
GO:0019900	kinase binding
GO:0019901	protein kinase binding
GO:0019902	phosphatase binding
GO:0035257	nuclear hormone receptor binding
GO:0043130	ubiquitin binding
GO:0071949	FAD binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006281	DNA repair
GO:0006351	transcription, DNA-templated
GO:0006606	protein import into nucleus
GO:0007623	circadian rhythm
GO:0009785	blue light signaling pathway
GO:0018298	protein-chromophore linkage
GO:0019915	lipid storage
GO:0032515	negative regulation of phosphoprotein phosphatase activity
GO:0032868	response to insulin
GO:0032922	circadian regulation of gene expression
GO:0042593	glucose homeostasis
GO:0042752	regulation of circadian rhythm
GO:0042754	negative regulation of circadian rhythm
GO:0043153	entrainment of circadian clock by photoperiod
GO:0045892	negative regulation of transcription, DNA-templated
GO:2000118	regulation of sodium-dependent phosphate transport
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
GO:2000850	negative regulation of glucocorticoid secretion