Version 5.4
Homo sapiens Protein: EXOSC1
Summary
InnateDB Protein IDBP-807045.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOSC1
Protein Name exosome component 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000473660
InnateDB Gene IDBG-84835 (EXOSC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 32 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
Biological Process
Cellular Component
GO:0000178 exosome (RNase complex)
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR019495 Exosome complex component CSL4
PFAM PF10447
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL R4GNH9
UniProt Splice Variant
Entrez Gene 51013
UniGene
RefSeq
HUGO HGNC:17286
OMIM 606493
CCDS
HPRD
IMGT
EMBL AL355490
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca