InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IFITM2

Summary

InnateDB Protein

IDBP-807140.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IFITM2

Protein Name

interferon induced transmembrane protein 2

Synonyms

1-8D; DSPA2c;

Species

Homo sapiens

Ensembl Protein

ENSP00000484689

InnateDB Gene

IDBG-16199 (IFITM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006955	immune response
GO:0009607	response to biotic stimulus
GO:0009615	response to virus
GO:0019221	cytokine-mediated signaling pathway
GO:0034341	response to interferon-gamma
GO:0035455	response to interferon-alpha
GO:0035456	response to interferon-beta
GO:0045071	negative regulation of viral genome replication
GO:0046597	negative regulation of viral entry into host cell
GO:0051607	defense response to virus
GO:0060337	type I interferon signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR007593 CD225/Dispanin family

PFAM

PF04505

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC136475 BC009696 CR541874 X57351

GenPept

AAH09696 CAA40625 CAG46672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca