Homo sapiens Protein: CLIC1
Summary
InnateDB Protein IDBP-807149.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLIC1
Protein Name chloride intracellular channel 1
Synonyms G6; NCC27;
Species Homo sapiens
Ensembl Protein ENSP00000479808
InnateDB Gene IDBG-125351 (CLIC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0006821 chloride transport
GO:0007165 signal transduction
GO:0034765 regulation of ion transmembrane transport
GO:0044070 regulation of anion transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0034707 chloride channel complex
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR002946 Intracellular chloride channel
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold
PFAM PF13098
PF13192
PF13462
PF13905
PRINTS PR01263
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5SRT3
UniProt Splice Variant
Entrez Gene 1192
UniGene
RefSeq NP_001274523
HUGO HGNC:2062
OMIM 602872
CCDS CCDS4719
HPRD
IMGT
EMBL AF034607 AF109197 AF129756 AJ012008 AK314014 AL662899 BA000025 BC064527 BC095469 CH471081 CR542071 U93205 X87689
GenPept AAC25675 AAD18073 AAD20437 AAD26137 AAH64527 AAH95469 BAB63376 BAG36725 CAA61020 CAB46078 CAG46868 CAI18417 EAX03503 EAX03504