InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DENND4C

Summary

InnateDB Protein

IDBP-807276.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DENND4C

Protein Name

DENN/MADD domain containing 4C

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000473565

InnateDB Gene

IDBG-52631 (DENND4C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0017112	Rab guanyl-nucleotide exchange factor activity

Biological Process

GO:0015031	protein transport
GO:0032313	regulation of Rab GTPase activity
GO:0032851	positive regulation of Rab GTPase activity
GO:0032869	cellular response to insulin stimulus
GO:0072659	protein localization to plasma membrane

Cellular Component

GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0030904	retromer complex
GO:0032593	insulin-responsive compartment

Protein Structure and Domains

PDB ID

InterPro

IPR001194 DENN domain
IPR005112 dDENN domain
IPR005113 uDENN domain

PFAM

PF02141
PF03455
PF03456

PRINTS

PIRSF

SMART

SM00799
SM00801
SM00800

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5VZ89

PhosphoSite

PhosphoSite-Q5VZ89

TrEMBL

X6R5W5

UniProt Splice Variant

Entrez Gene

55667

UniGene

RefSeq

NP_060395

HUGO

HGNC:26079

OMIM

CCDS

CCDS6491

HPRD

IMGT

EMBL

AK000627 AK001046 AK002020 AK025705 AK125842 AL161909 AL391834 AL834521 CH471071 CR627367

GenPept

BAA91294 BAA91478 BAA92039 BAB15221 BAC86313 CAD39177 CAH10466 CAH70581 CAM21138 CAM21139 CAM21140 CAM21141 CAM21148 EAW58645