Version 5.4
Homo sapiens Gene: DENND4C
Summary
InnateDB Gene IDBG-52631.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DENND4C
Gene Name DENN/MADD domain containing 4C
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137145
Encoded Proteins
IDBP-52641
DENN/MADD domain containing 4C
IDBP-52643
DENN/MADD domain containing 4C
IDBP-52645
DENN/MADD domain containing 4C
IDBP-807288
DENN/MADD domain containing 4C
IDBP-807276
DENN/MADD domain containing 4C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:19230435-19373545
Strand Forward strand
Band p22.1
Transcripts
ENST00000380437
ENST00000380427 ENSP00000369792
ENST00000361024 ENSP00000354301
ENST00000380424 ENSP00000369789
ENST00000494124 ENSP00000473273
ENST00000602925 ENSP00000473565
ENST00000602708
ENST00000602442
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0015031 protein transport
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:0032869 cellular response to insulin stimulus
GO:0072659 protein localization to plasma membrane
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0030904 retromer complex
GO:0032593 insulin-responsive compartment
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038024
View Gene Order
ENSBTAG00000003097
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.249591 Hs.701821
RefSeq NM_017925 XM_006716804
HUGO
OMIM
CCDS CCDS6491
HPRD 12927
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca