InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RFX3

Summary

InnateDB Protein

IDBP-807427.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RFX3

Protein Name

regulatory factor X, 3 (influences HLA class II expression)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000482598

InnateDB Gene

IDBG-45438 (RFX3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0031018	endocrine pancreas development
GO:0042384	cilium assembly
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048469	cell maturation
GO:0050796	regulation of insulin secretion
GO:0060285	cilium-dependent cell motility
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
GO:2000078	positive regulation of type B pancreatic cell development