Version 5.4
Homo sapiens Protein: ZP4
Summary
InnateDB Protein IDBP-807620.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZP4
Protein Name zona pellucida glycoprotein 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000482304
InnateDB Gene IDBG-107656 (ZP4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0032190 acrosin binding
Biological Process
GO:0002922 positive regulation of humoral immune response
GO:0007338 single fertilization
GO:0007339 binding of sperm to zona pellucida
GO:0010737 protein kinase A signaling
GO:0032504 multicellular organism reproduction
GO:0035556 intracellular signal transduction
GO:0042102 positive regulation of T cell proliferation
GO:0045860 positive regulation of protein kinase activity
GO:0060478 acrosomal vesicle exocytosis
GO:0070528 protein kinase C signaling
GO:2000344 positive regulation of acrosome reaction
GO:2000360 negative regulation of binding of sperm to zona pellucida
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000519 P-type trefoil
IPR001507 Zona pellucida domain
PFAM PF00088
PF00100
PRINTS PR00023
PIRSF
SMART SM00018
SM00241
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 57829
UniGene
RefSeq NP_067009
HUGO HGNC:15770
OMIM 613514
CCDS CCDS1615
HPRD
IMGT
EMBL AK314151 AL359924 BC069521 CH471098 U05781
GenPept AAA74391 AAH69521 BAG36838 CAI22066 EAW70072

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca