Homo sapiens Protein: CPSF1
Summary
InnateDB Protein IDBP-807651.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPSF1
Protein Name cleavage and polyadenylation specific factor 1, 160kDa
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000478145
InnateDB Gene IDBG-40804 (CPSF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 57 [view]
Protein-Protein 55 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006378 mRNA polyadenylation
GO:0006379 mRNA cleavage
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
Protein Structure and Domains
PDB ID
InterPro IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminal
PFAM PF03178
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q10570
PhosphoSite PhosphoSite-Q10570
TrEMBL Q9C0J6
UniProt Splice Variant
Entrez Gene 29894
UniGene
RefSeq
HUGO HGNC:2324
OMIM 606027
CCDS CCDS34966
HPRD
IMGT
EMBL AB046744 AF205589 BC017232 CH471162 U37012
GenPept AAC50293 AAH17232 BAB21613 EAW82106 EAW82107 EAW82108