InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTP4A2

Summary

InnateDB Protein

IDBP-807883.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTP4A2

Protein Name

protein tyrosine phosphatase type IVA, member 2

Synonyms

HH13; HH7-2; HU-PP-1; OV-1; PRL-2; PRL2; ptp-IV1a; ptp-IV1b; PTP4A; PTPCAAX2;

Species

Homo sapiens

Ensembl Protein

ENSP00000473490

InnateDB Gene

IDBG-95523 (PTP4A2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004727	prenylated protein tyrosine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

GO:0005737	cytoplasm
GO:0005769	early endosome
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q12974

PhosphoSite

PhosphoSite-Q12974

TrEMBL

E9PMY3

UniProt Splice Variant

Entrez Gene

8073

UniGene

RefSeq

NP_001182029

HUGO

HGNC:9635

OMIM

601584

CCDS

CCDS59193

HPRD

IMGT

EMBL

AF208850 AK292703 AK297280 AL136115 BC070182 CH471059 L39000 L48722 L48723 L48937 U14603 U48297

GenPept

AAA90979 AAB39331 AAB40598 AAB42169 AAB42170 AAB59575 AAF64264 AAH70182 BAF85392 BAG59751 CAI21726 EAX07578 EAX07579 EAX07582 EAX07583