InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: APBB1

Summary

InnateDB Protein

IDBP-807892.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APBB1

Protein Name

amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)

Synonyms

FE65; MGC:9072; RIR;

Species

Homo sapiens

Ensembl Protein

ENSP00000476846

InnateDB Gene

IDBG-28785 (APBB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 84 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	84 [view]
Protein-Protein	83 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001540	beta-amyloid binding
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0042393	histone binding
GO:0070064	proline-rich region binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0006974	cellular response to DNA damage stimulus
GO:0007050	cell cycle arrest
GO:0007165	signal transduction
GO:0007409	axonogenesis
GO:0030308	negative regulation of cell growth
GO:0043065	positive regulation of apoptotic process
GO:0043967	histone H4 acetylation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0050760	negative regulation of thymidylate synthase biosynthetic process