Homo sapiens Protein: POLE
Summary
InnateDB Protein IDBP-807979.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLE
Protein Name polymerase (DNA directed), epsilon, catalytic subunit
Synonyms CRCS12; FILS; POLE1;
Species Homo sapiens
Ensembl Protein ENSP00000480727
InnateDB Gene IDBG-65706 (POLE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003887 DNA-directed DNA polymerase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR013697 DNA polymerase epsilon, catalytic subunit A, C-terminal
PFAM PF08490
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 5426
UniGene
RefSeq
HUGO HGNC:9177
OMIM 174762
CCDS
HPRD
IMGT
EMBL
GenPept