Version 5.4
Homo sapiens Protein: UBE2W
Summary
InnateDB Protein IDBP-808024.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2W
Protein Name ubiquitin-conjugating enzyme E2W (putative)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000473561
InnateDB Gene IDBG-25727 (UBE2W)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 75 experimentally validated interaction(s) in this database.
Experimentally validated
Total 75 [view]
Protein-Protein 74 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006281 DNA repair
GO:0006513 protein monoubiquitination
GO:0006515 misfolded or incompletely synthesized protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070979 protein K11-linked ubiquitination
GO:0071218 cellular response to misfolded protein
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
PFAM PF00179
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96B02
PhosphoSite PhosphoSite-Q96B02
TrEMBL
UniProt Splice Variant
Entrez Gene 55284
UniGene
RefSeq
HUGO HGNC:25616
OMIM 614277
CCDS
HPRD
IMGT
EMBL AC022826 AK001873 AK021735 AK024050 AK295792 AY948289 BC016326 CH471068 CR457275
GenPept AAH16326 AAY24555 BAA91954 BAB13883 BAB14800 BAG58613 CAG33556 EAW87009 EAW87011

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca