InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FKBP8

Summary

InnateDB Protein

IDBP-808114.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FKBP8

Protein Name

FK506 binding protein 8, 38kDa

Synonyms

FKBP38; FKBPr38;

Species

Homo sapiens

Ensembl Protein

ENSP00000476767

InnateDB Gene

IDBG-38336 (FKBP8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 99 experimentally validated interaction(s) in this database.

Experimentally validated
Total	99 [view]
Protein-Protein	99 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005515	protein binding
GO:0005528	FK506 binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0001708	cell fate specification
GO:0006457	protein folding
GO:0006915	apoptotic process
GO:0007224	smoothened signaling pathway
GO:0009953	dorsal/ventral pattern formation
GO:0010468	regulation of gene expression
GO:0016032	viral process
GO:0021904	dorsal/ventral neural tube patterning
GO:0021915	neural tube development
GO:0030510	regulation of BMP signaling pathway
GO:0030513	positive regulation of BMP signaling pathway
GO:0035264	multicellular organism growth
GO:0035556	intracellular signal transduction
GO:0043010	camera-type eye development
GO:0043066	negative regulation of apoptotic process
GO:0061077	chaperone-mediated protein folding

Cellular Component

GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030176	integral component of endoplasmic reticulum membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00254
PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q14318