InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC37A4

Summary

InnateDB Protein

IDBP-808211.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC37A4

Protein Name

solute carrier family 37 (glucose-6-phosphate transporter), member 4

Synonyms

G6PT1; G6PT2; G6PT3; GSD1b; GSD1c; GSD1d; TRG-19; TRG19;

Species

Homo sapiens

Ensembl Protein

ENSP00000476176

InnateDB Gene

IDBG-74181 (SLC37A4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	2 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0015152	glucose-6-phosphate transmembrane transporter activity

Biological Process

GO:0001780	neutrophil homeostasis
GO:0001816	cytokine production
GO:0002318	myeloid progenitor cell differentiation
GO:0005977	glycogen metabolic process
GO:0006089	lactate metabolic process
GO:0006641	triglyceride metabolic process
GO:0006810	transport
GO:0006874	cellular calcium ion homeostasis
GO:0007584	response to nutrient
GO:0008202	steroid metabolic process
GO:0009749	response to glucose
GO:0014070	response to organic cyclic compound
GO:0015760	glucose-6-phosphate transport
GO:0030593	neutrophil chemotaxis
GO:0032682	negative regulation of chemokine production
GO:0035166	post-embryonic hemopoiesis
GO:0042593	glucose homeostasis
GO:0042632	cholesterol homeostasis
GO:0043085	positive regulation of catalytic activity
GO:0045730	respiratory burst
GO:0055085	transmembrane transport

Cellular Component

GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR000849 Sugar phosphate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain

PFAM

PF07690

PRINTS

PIRSF

PIRSF002808

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite