InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CERS1

Summary

InnateDB Protein

IDBP-808389.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CERS1

Protein Name

ceramide synthase 1

Synonyms

DORV; DTGA3; LAG1; LASS1; RAI; UOG1;

Species

Homo sapiens

Ensembl Protein

ENSP00000485308

InnateDB Gene

IDBG-304491 (CERS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0050291	sphingosine N-acyltransferase activity

Biological Process

GO:0006665	sphingolipid metabolic process
GO:0030148	sphingolipid biosynthetic process
GO:0035690	cellular response to drug
GO:0036146	cellular response to mycotoxin
GO:0044281	small molecule metabolic process
GO:0046513	ceramide biosynthetic process
GO:0051974	negative regulation of telomerase activity
GO:0071492	cellular response to UV-A
GO:0072721	cellular response to dithiothreitol

Cellular Component

GO:0000139	Golgi membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle