Version 5.4
Homo sapiens Protein: HBXIP
Summary
InnateDB Protein IDBP-808553.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HBXIP
Protein Name late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Synonyms HBXIP; XIP;
Species Homo sapiens
Ensembl Protein ENSP00000473439
InnateDB Gene IDBG-100979 (HBXIP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 19 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0032947 protein complex scaffold
Biological Process
GO:0008361 regulation of cell size
GO:0009615 response to virus
GO:0019079 viral genome replication
GO:0032008 positive regulation of TOR signaling
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0061462 protein localization to lysosome
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005829 cytosol
GO:0071986 Ragulator complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43504
PhosphoSite PhosphoSite-O43504
TrEMBL R4GMU8
UniProt Splice Variant
Entrez Gene 10542
UniGene
RefSeq
HUGO HGNC:17955
OMIM 608521
CCDS
HPRD
IMGT
EMBL AF029890 AL390797 AY623819 BC062619 CR456866 CR542130
GenPept AAC52032 AAH62619 AAV30683 CAG33147 CAG46927 CAH71488

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca