InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PHF17

Summary

InnateDB Protein

IDBP-808669.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PHF17

Protein Name

jade family PHD finger 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000483219

InnateDB Gene

IDBG-37885 (PHF17)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	31 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001105	RNA polymerase II transcription coactivator activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006325	chromatin organization
GO:0006351	transcription, DNA-templated
GO:0006915	apoptotic process
GO:0006950	response to stress
GO:0030308	negative regulation of cell growth
GO:0043966	histone H3 acetylation
GO:0043981	histone H4-K5 acetylation
GO:0043982	histone H4-K8 acetylation
GO:0043983	histone H4-K12 acetylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle

Cellular Component

GO:0000123	histone acetyltransferase complex
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0045171	intercellular bridge

Protein Structure and Domains

PDB ID

InterPro

IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR019542 Enhancer of polycomb-like, N-terminal
IPR019787 Zinc finger, PHD-finger

PFAM

PF10513
PF00628

PRINTS

PIRSF

SMART

SM00249

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite