InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DHRS3

Summary

InnateDB Protein

IDBP-808769.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DHRS3

Protein Name

dehydrogenase/reductase (SDR family) member 3

Synonyms

DD83.1; RDH17; retSDR1; Rsdr1; SDR1; SDR16C1;

Species

Homo sapiens

Ensembl Protein

ENSP00000480439

InnateDB Gene

IDBG-90211 (DHRS3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004745	retinol dehydrogenase activity
GO:0009055	electron carrier activity
GO:0016491	oxidoreductase activity
GO:0052650	NADP-retinol dehydrogenase activity

Biological Process

GO:0001523	retinoid metabolic process
GO:0003151	outflow tract morphogenesis
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0030278	regulation of ossification
GO:0042572	retinol metabolic process
GO:0048387	negative regulation of retinoic acid receptor signaling pathway
GO:0055114	oxidation-reduction process
GO:0060021	palate development
GO:0060349	bone morphogenesis
GO:0060411	cardiac septum morphogenesis

Cellular Component

GO:0016021	integral component of membrane
GO:0042622	photoreceptor outer segment membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR003869 Polysaccharide biosynthesis protein, CapD-like domain
IPR013968 Polyketide synthase, KR
IPR020842 Polyketide synthase/Fatty acid synthase, KR

PFAM

PF00106
PF02719
PF08659

PRINTS

PR00080
PR00081

PIRSF

PIRSF000126

SMART

SM00822

TIGRFAMs

Post-translational Modifications

Modification

Cross-References