InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DOC2A

Summary

InnateDB Protein

IDBP-808773.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DOC2A

Protein Name

double C2-like domains, alpha

Synonyms

Doc2;

Species

Homo sapiens

Ensembl Protein

ENSP00000482870

InnateDB Gene

IDBG-25372 (DOC2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0005544	calcium-dependent phospholipid binding

Biological Process

GO:0007268	synaptic transmission
GO:0007399	nervous system development
GO:0017158	regulation of calcium ion-dependent exocytosis

Cellular Component

GO:0005764	lysosome
GO:0030054	cell junction
GO:0030672	synaptic vesicle membrane
GO:0043005	neuron projection

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR001565 Synaptotagmin
IPR014638 Double C2 protein, alpha/beta/gamma type

PFAM

PF00168

PRINTS

PR00360
PR00399

PIRSF

PIRSF036931

SMART

SM00239

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H3BU41

UniProt Splice Variant

Entrez Gene

8448

UniGene

RefSeq

NP_001268992

HUGO

HGNC:2985

OMIM

604567

CCDS

CCDS10666

HPRD

IMGT

EMBL

AC093512 BC041769 BC055284 BC063436 D31897

GenPept

AAH41769 AAH55284 AAH63436 BAA06695