Version 5.4
Homo sapiens Protein: MCL1
Summary
InnateDB Protein IDBP-809708.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCL1
Protein Name myeloid cell leukemia 1
Synonyms bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM;
Species Homo sapiens
Ensembl Protein ENSP00000477624
InnateDB Gene IDBG-102145 (MCL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 87 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 87 [view]
Protein-Protein 82 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042981 regulation of apoptotic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002475 Bcl2-like
IPR013281 Apoptosis regulator, Mcl-1
IPR026298 Blc2 family
PFAM PF00452
PRINTS PR01866
PR01862
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4170
UniGene
RefSeq NP_001184249
HUGO HGNC:6943
OMIM 159552
CCDS CCDS72909
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca