InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NR2C2

Summary

InnateDB Protein

IDBP-809730.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NR2C2

Protein Name

nuclear receptor subfamily 2, group C, member 2

Synonyms

TAK1; TR4;

Species

Homo sapiens

Ensembl Protein

ENSP00000483059

InnateDB Gene

IDBG-20458 (NR2C2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.

Experimentally validated
Total	41 [view]
Protein-Protein	40 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007283	spermatogenesis
GO:0021549	cerebellum development
GO:0040019	positive regulation of embryonic development
GO:0043401	steroid hormone mediated signaling pathway
GO:0048520	positive regulation of behavior
GO:0051321	meiotic cell cycle

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR008946 Nuclear hormone receptor, ligand-binding

PFAM

PF00104
PF00105

PRINTS

PR00047
PR00398

PIRSF

SMART

SM00430
SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt