Version 5.4
Homo sapiens Protein: LAP3
Summary
InnateDB Protein IDBP-809778.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LAP3
Protein Name leucine aminopeptidase 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000476028
InnateDB Gene IDBG-10959 (LAP3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal
IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal
IPR011356 Leucine aminopeptidase/peptidase B
PFAM PF00883
PF02789
PRINTS PR00481
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P28838
PhosphoSite PhosphoSite-P28838
TrEMBL
UniProt Splice Variant
Entrez Gene 51056
UniGene
RefSeq
HUGO HGNC:18449
OMIM 170250
CCDS
HPRD
IMGT
EMBL AF061738 AK022055 AK298613 BC006199 BC065564 CR457128
GenPept AAD17527 AAH06199 AAH65564 BAG51065 BAG60795 CAG33409

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca