InnateDB Protein
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IDBP-810407.1
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RRM2
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Protein Name
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ribonucleotide reductase M2
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Synonyms
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R2; RR2; RR2M;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000484183
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InnateDB Gene
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IDBG-28300 (RRM2)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
16
[view]
|
Protein-Protein |
15
[view]
|
Protein-DNA |
0
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Protein-RNA |
1
[view]
|
DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
5 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0004748
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ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
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GO:0005515
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protein binding
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GO:0046872
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metal ion binding
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Biological Process |
GO:0000082
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G1/S transition of mitotic cell cycle
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GO:0000083
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regulation of transcription involved in G1/S transition of mitotic cell cycle
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GO:0000278
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mitotic cell cycle
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GO:0006260
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DNA replication
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GO:0009186
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deoxyribonucleoside diphosphate metabolic process
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GO:0009263
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deoxyribonucleotide biosynthetic process
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GO:0015949
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nucleobase-containing small molecule interconversion
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GO:0044281
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small molecule metabolic process
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GO:0055086
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nucleobase-containing small molecule metabolic process
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GO:0055114
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oxidation-reduction process
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Cellular Component |
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PDB ID |
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InterPro |
IPR000358
Ribonucleotide reductase small subunit
IPR009078
Ferritin-like superfamily
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PFAM |
PF00268
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q9UKM0
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UniProt Splice Variant |
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Entrez Gene |
6241
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UniGene |
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RefSeq |
NP_001159403
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HUGO |
HGNC:10452
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OMIM |
180390
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CCDS |
CCDS54334
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HPRD |
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IMGT |
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EMBL |
AC104794
AC118058
AF149206
AK092671
AK123010
AK313719
AY032750
BC001886
BC028932
BC030154
DA477511
S40301
X59618
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GenPept |
AAA09577
AAD53261
AAH01886
AAH28932
AAH30154
AAK51163
AAX93099
BAG36462
BAG52588
BAG53847
CAA42181
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