InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NDFIP2

Summary

InnateDB Protein

IDBP-810678.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDFIP2

Protein Name

Nedd4 family interacting protein 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000480798

InnateDB Gene

IDBG-41123 (NDFIP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0050699	WW domain binding

Biological Process

GO:0007165	signal transduction
GO:0010629	negative regulation of gene expression
GO:0031398	positive regulation of protein ubiquitination
GO:0032410	negative regulation of transporter activity
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051224	negative regulation of protein transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0016021	integral component of membrane
GO:0032585	multivesicular body membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR019325 NEDD4/BSD2

PFAM

PF10176

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB032991 AB097019 AB097028 AB097029 AB097030 AB097031 AK001723 AL136442 AL355603 BC021988 BC026126

GenPept

AAH21988 AAH26126 BAA86479 BAA91863 BAC77372 BAC77381 BAC77382 BAC77383 BAC77384 CAH71782 CAH73355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca