Version 5.4
Homo sapiens Gene: NDFIP2
Summary
InnateDB Gene IDBG-41123.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDFIP2
Gene Name Nedd4 family interacting protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102471
Encoded Proteins
IDBP-41125
Nedd4 family interacting protein 2
IDBP-477233
Nedd4 family interacting protein 2
IDBP-482322
Nedd4 family interacting protein 2
IDBP-810676
Nedd4 family interacting protein 2
IDBP-810678
Nedd4 family interacting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:79481124-79556075
Strand Forward strand
Band q31.1
Transcripts
ENST00000218652 ENSP00000218652
ENST00000487865 ENSP00000419200
ENST00000465762 ENSP00000419776
ENST00000494647
ENST00000620924 ENSP00000480881
ENST00000612570 ENSP00000480798
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0050699 WW domain binding
Biological Process
GO:0007165 signal transduction
GO:0010629 negative regulation of gene expression
GO:0031398 positive regulation of protein ubiquitination
GO:0032410 negative regulation of transporter activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051224 negative regulation of protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0032585 multivesicular body membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000053253
View Gene Order
ENSBTAG00000014227
Not yet available
Cross-References
SwissProt Q9NV92
TrEMBL B4DGY6 H0Y8A7
UniProt Splice Variant
Entrez Gene 54602
UniGene Hs.525093 Hs.597300 Hs.608520
RefSeq NM_001161407 NM_019080 XM_006719840
HUGO HGNC:18537
OMIM 610041
CCDS CCDS31998
HPRD
IMGT
EMBL AB032991 AB097019 AB097028 AB097029 AB097030 AB097031 AK001723 AK294839 AL136442 AL355603 BC021988 BC026126
GenPept AAH21988 AAH26126 BAA86479 BAA91863 BAC77372 BAC77381 BAC77382 BAC77383 BAC77384 BAG57947 CAH71782 CAH73355
RNA Seq Atlas 54602

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca