InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: WAPAL

Summary

InnateDB Protein

IDBP-811012.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WAPAL

Protein Name

wings apart-like homolog (Drosophila)

Synonyms

FOE; KIAA0261; WAPL;

Species

Homo sapiens

Ensembl Protein

ENSP00000481451

InnateDB Gene

IDBG-80903 (WAPAL)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	39 [view]
Protein-Protein	37 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0007067	mitotic nuclear division
GO:0008156	negative regulation of DNA replication
GO:0016032	viral process
GO:0035562	negative regulation of chromatin binding
GO:0045875	negative regulation of sister chromatid cohesion
GO:0071168	protein localization to chromatin
GO:0071922	regulation of cohesin localization to chromatin

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0000785	chromatin
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0008278	cohesin complex
GO:0015630	microtubule cytoskeleton
GO:0043231	intracellular membrane-bounded organelle