InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: WAPAL

Summary

InnateDB Gene

IDBG-80903.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WAPAL

Gene Name

wings apart-like homolog (Drosophila)

Synonyms

FOE; KIAA0261; WAPL

Species

Homo sapiens

Ensembl Gene

ENSG00000062650

Encoded Proteins

IDBP-80909

wings apart-like homolog (Drosophila)

IDBP-80911

wings apart-like homolog (Drosophila)

IDBP-80915

wings apart-like homolog (Drosophila)

IDBP-811012

wings apart-like homolog (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:86435256-86521815

Strand

Reverse strand

Band

q23.2

Transcripts

ENST00000298767	ENSP00000298767
ENST00000263070	ENSP00000263070
ENST00000372075	ENSP00000361145
ENST00000484070
ENST00000495124
ENST00000489996
ENST00000618527	ENSP00000481451

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	39 [view]
Protein-Protein	37 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0007067	mitotic nuclear division
GO:0008156	negative regulation of DNA replication
GO:0009636	response to toxic substance
GO:0016032	viral process
GO:0035562	negative regulation of chromatin binding
GO:0045875	negative regulation of sister chromatid cohesion
GO:0048146	positive regulation of fibroblast proliferation
GO:0051983	regulation of chromosome segregation
GO:0060623	regulation of chromosome condensation
GO:0071168	protein localization to chromatin
GO:0071922	regulation of cohesin localization to chromatin

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0000785	chromatin
GO:0000795	synaptonemal complex
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0008278	cohesin complex
GO:0015630	microtubule cytoskeleton
GO:0043231	intracellular membrane-bounded organelle