Homo sapiens Protein: ITSN2
Summary
InnateDB Protein IDBP-811470.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITSN2
Protein Name intersectin 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000479408
InnateDB Gene IDBG-33600 (ITSN2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
Experimentally validated
Total 86 [view]
Protein-Protein 86 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR000219 Dbl homology (DH) domain
IPR000261 EPS15 homology (EH)
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR002048 EF-hand domain
IPR011511 Variant SH3 domain
PFAM PF00168
PF00621
PF00018
PF14604
PF00169
PF00036
PF13202
PF13405
PF07653
PRINTS PR00360
PR00452
PIRSF
SMART SM00239
SM00325
SM00027
SM00326
SM00233
SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q53TM3
UniProt Splice Variant
Entrez Gene 50618
UniGene
RefSeq
HUGO HGNC:6184
OMIM 604464
CCDS
HPRD
IMGT
EMBL AC008073 AC009228
GenPept AAY14668