InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAG2

Summary

InnateDB Protein

IDBP-811525.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAG2

Protein Name

recombination activating gene 2

Synonyms

RAG-2;

Species

Homo sapiens

Ensembl Protein

ENSP00000478672

InnateDB Gene

IDBG-40186 (RAG2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008270	zinc ion binding
GO:0035064	methylated histone binding
GO:0035091	phosphatidylinositol binding
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding

Biological Process

GO:0002326	B cell lineage commitment
GO:0002331	pre-B cell allelic exclusion
GO:0002358	B cell homeostatic proliferation
GO:0002360	T cell lineage commitment
GO:0006310	DNA recombination
GO:0016568	chromatin modification
GO:0030183	B cell differentiation
GO:0030217	T cell differentiation
GO:0033077	T cell differentiation in thymus
GO:0033151	V(D)J recombination
GO:0046622	positive regulation of organ growth