InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: THBS2

Summary

InnateDB Protein

IDBP-811696.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

THBS2

Protein Name

thrombospondin 2

Synonyms

TSP2;

Species

Homo sapiens

Ensembl Protein

ENSP00000482784

InnateDB Gene

IDBG-99215 (THBS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008201	heparin binding

Biological Process

GO:0007155	cell adhesion
GO:0016525	negative regulation of angiogenesis

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR000884 Thrombospondin, type 1 repeat
IPR001007 von Willebrand factor, type C
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR003367 Thrombospondin, type 3-like repeat
IPR008859 Thrombospondin, C-terminal
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR028974 TSP type-3 repeat

PFAM