InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IST1

Summary

InnateDB Protein

IDBP-811731.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IST1

Protein Name

increased sodium tolerance 1 homolog (yeast)

Synonyms

OLC1;

Species

Homo sapiens

Ensembl Protein

ENSP00000475853

InnateDB Gene

IDBG-41285 (IST1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0032403	protein complex binding
GO:0090541	MIT domain binding

Biological Process

GO:0000910	cytokinesis
GO:0008104	protein localization
GO:0009838	abscission
GO:0019076	viral release from host cell
GO:0045184	establishment of protein localization
GO:0045862	positive regulation of proteolysis
GO:0046745	viral capsid secondary envelopment
GO:0051301	cell division

Cellular Component

GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
GO:0005813	centrosome
GO:0005829	cytosol
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030496	midbody
GO:0070062	extracellular vesicular exosome
GO:0090543	Flemming body

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-P53990

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB097052 AC009127 AC010653 AK057258 AK293022 AK293040 AK301918 BC000116 BC000430 BC004359 BC103745 D79996

GenPept

AAH00116 AAH00430 AAH04359 AAI03746 BAA11491 BAC77405 BAF85711 BAF85729 BAG51894 BAG63341

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca