InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BNIP2

Summary

InnateDB Protein

IDBP-811913.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BNIP2

Protein Name

BCL2/adenovirus E1B 19kDa interacting protein 2

Synonyms

BNIP-2; NIP2;

Species

Homo sapiens

Ensembl Protein

ENSP00000475320

InnateDB Gene

IDBG-14641 (BNIP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.

Experimentally validated
Total	20 [view]
Protein-Protein	19 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0006915	apoptotic process
GO:0042692	muscle cell differentiation
GO:0043066	negative regulation of apoptotic process
GO:0043547	positive regulation of GTPase activity
GO:0051149	positive regulation of muscle cell differentiation

Cellular Component

GO:0005635	nuclear envelope
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043231	intracellular membrane-bounded organelle
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001251 CRAL-TRIO domain
IPR022181 Bcl2-/adenovirus E1B 19kDa-interacting protein 2

PFAM

PF00650
PF13716
PF12496

PRINTS

PIRSF

SMART

SM00516

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q12982

PhosphoSite

PhosphoSite-Q12982

TrEMBL

UniProt Splice Variant

Entrez Gene

663

UniGene

RefSeq

HUGO

HGNC:1083

OMIM

603292

CCDS

HPRD

IMGT

EMBL

AC092755 AK299628 AY268590 BC002461 U15173

GenPept

AAC00021 AAH02461 AAP03429 BAG61556