Version 5.4
Homo sapiens Protein: BNIP2
Summary
InnateDB Protein IDBP-811921.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BNIP2
Protein Name BCL2/adenovirus E1B 19kDa interacting protein 2
Synonyms BNIP-2; NIP2;
Species Homo sapiens
Ensembl Protein ENSP00000479818
InnateDB Gene IDBG-14641 (BNIP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006915 apoptotic process
GO:0042692 muscle cell differentiation
GO:0043066 negative regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0051149 positive regulation of muscle cell differentiation
Cellular Component
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001251 CRAL-TRIO domain
IPR022181 Bcl2-/adenovirus E1B 19kDa-interacting protein 2
PFAM PF00650
PF13716
PF12496
PRINTS
PIRSF
SMART SM00516
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3KN59
UniProt Splice Variant
Entrez Gene 663
UniGene
RefSeq NP_004321
HUGO HGNC:1083
OMIM 603292
CCDS CCDS10174
HPRD
IMGT
EMBL AC092755 AK299628 AY268590 BC002461 U15173
GenPept AAC00021 AAH02461 AAP03429 BAG61556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca