InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HNF4A

Summary

InnateDB Protein

IDBP-811995.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HNF4A

Protein Name

hepatocyte nuclear factor 4, alpha

Synonyms

HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14;

Species

Homo sapiens

Ensembl Protein

ENSP00000476310

InnateDB Gene

IDBG-76498 (HNF4A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2332 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	2332 [view]
Protein-Protein	87 [view]
Protein-DNA	2243 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001628 Zinc finger, nuclear hormone receptor-type

PFAM

PF00105

PRINTS

PR00047

PIRSF

SMART

SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B9VVT8

UniProt Splice Variant

Entrez Gene

3172

UniGene

RefSeq

HUGO

HGNC:5024

OMIM

600281

CCDS

HPRD

IMGT

EMBL

AL117382 AL132772 FJ608822

GenPept

ACM50922