Version 5.4
Homo sapiens Protein: SPTBN1
Summary
InnateDB Protein IDBP-812582.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPTBN1
Protein Name spectrin, beta, non-erythrocytic 1
Synonyms betaSpII; ELF; HEL102; SPTB2;
Species Homo sapiens
Ensembl Protein ENSP00000479037
InnateDB Gene IDBG-51911 (SPTBN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 100 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 100 [view]
Protein-Protein 100 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0008091 spectrin
Protein Structure and Domains
PDB ID
InterPro IPR001605 Pleckstrin homology domain, spectrin-type
IPR001715 Calponin homology domain
IPR001849 Pleckstrin homology domain
IPR002017 Spectrin repeat
IPR016343 Spectrin, beta subunit
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
PFAM PF00307
PF00169
PF00435
PF11971
PRINTS PR00683
PIRSF PIRSF002297
SMART SM00033
SM00233
SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q53RC4
UniProt Splice Variant
Entrez Gene 6711
UniGene
RefSeq
HUGO HGNC:11275
OMIM 182790
CCDS
HPRD
IMGT
EMBL AC092839 AC093110
GenPept AAX93104

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca