InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDOST

Summary

InnateDB Protein

IDBP-812702.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDOST

Protein Name

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)

Synonyms

AGER1; CDG1R; OKSWcl45; OST; OST48; WBP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000473655

InnateDB Gene

IDBG-409236 (DDOST)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004576	oligosaccharyl transferase activity
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005515	protein binding

Biological Process

GO:0006412	translation
GO:0006486	protein glycosylation
GO:0006487	protein N-linked glycosylation
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0018279	protein N-linked glycosylation via asparagine
GO:0034097	response to cytokine
GO:0042110	T cell activation
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0045087	innate immune response

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0008250	oligosaccharyltransferase complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0043234	protein complex