InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EHD1

Summary

InnateDB Protein

IDBP-812887.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EHD1

Protein Name

EH-domain containing 1

Synonyms

H-PAST; HPAST1; PAST; PAST1;

Species

Homo sapiens

Ensembl Protein

ENSP00000479153

InnateDB Gene

IDBG-55744 (EHD1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	54 [view]
Protein-Protein	53 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0017137	Rab GTPase binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0007596	blood coagulation
GO:0010886	positive regulation of cholesterol storage
GO:0016197	endosomal transport
GO:0031175	neuron projection development
GO:0032456	endocytic recycling
GO:0034383	low-density lipoprotein particle clearance
GO:0042632	cholesterol homeostasis
GO:0051260	protein homooligomerization
GO:1901741	positive regulation of myoblast fusion
GO:1990090	cellular response to nerve growth factor stimulus
GO:2001137	positive regulation of endocytic recycling

Cellular Component

GO:0005768	endosome
GO:0005769	early endosome
GO:0005811	lipid particle
GO:0005886	plasma membrane
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0030139	endocytic vesicle
GO:0031095	platelet dense tubular network membrane
GO:0031901	early endosome membrane
GO:0048471	perinuclear region of cytoplasm
GO:0055038	recycling endosome membrane
GO:0070062	extracellular vesicular exosome