InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AKR1A1

Summary

InnateDB Protein

IDBP-813069.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AKR1A1

Protein Name

aldo-keto reductase family 1, member A1 (aldehyde reductase)

Synonyms

ALDR1; ALR; ARM; DD3; HEL-S-6;

Species

Homo sapiens

Ensembl Protein

ENSP00000480713

InnateDB Gene

IDBG-97967 (AKR1A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004032	alditol:NADP+ 1-oxidoreductase activity
GO:0009055	electron carrier activity
GO:0016491	oxidoreductase activity

Biological Process

GO:0006006	glucose metabolic process
GO:0006081	cellular aldehyde metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005615	extracellular space
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR020471 Aldo/keto reductase subgroup
IPR023210 NADP-dependent oxidoreductase domain

PFAM

PF00248

PRINTS

PR00069

PIRSF

PIRSF000097

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

V9HWI0

UniProt Splice Variant

Entrez Gene

10327

UniGene

RefSeq

NP_697021

HUGO

HGNC:380

OMIM

103830

CCDS

CCDS523

HPRD

IMGT

EMBL

AF036680 AF036681 AF036682 AF036683 AF112484 AF112485 AK293083 AL355480 BC000670 BC005394 BT007003 CH471059 CR457010 EU668319 EU794588 J04794

GenPept

AAA51711 AAB92369 AAF01260 AAH00670 AAH05394 AAP35649 ACF94472 ACJ13642 BAF85772 CAG33291 CAI22459 EAX06970 EAX06971 EAX06972 EAX06974