Homo sapiens Protein: REC8
Summary
InnateDB Protein IDBP-813149.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REC8
Protein Name REC8 meiotic recombination protein
Synonyms HR21spB; REC8L1; Rec8p;
Species Homo sapiens
Ensembl Protein ENSP00000482546
InnateDB Gene IDBG-3616 (REC8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0001556 oocyte maturation
GO:0007062 sister chromatid cohesion
GO:0007126 meiotic nuclear division
GO:0007129 synapsis
GO:0007131 reciprocal meiotic recombination
GO:0007141 male meiosis I
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0009566 fertilization
GO:0030999 linear element assembly
GO:0072520 seminiferous tubule development
Cellular Component
GO:0000228 nuclear chromosome
GO:0000778 condensed nuclear chromosome kinetochore
GO:0000780 condensed nuclear chromosome, centromeric region
GO:0000794 condensed nuclear chromosome
GO:0000795 synaptonemal complex
GO:0000800 lateral element
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
GO:0030893 meiotic cohesin complex
GO:0034991 nuclear meiotic cohesin complex
Protein Structure and Domains
PDB ID
InterPro IPR006909 Rad21/Rec8-like protein, C-terminal, eukaryotic
IPR006910 Rad21/Rec8-like protein, N-terminal
PFAM PF04824
PF04825
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95072
PhosphoSite PhosphoSite-O95072
TrEMBL H0YMV7
UniProt Splice Variant
Entrez Gene 9985
UniGene
RefSeq
HUGO HGNC:16879
OMIM 608193
CCDS CCDS41932
HPRD
IMGT
EMBL AF006264 AK001435 AK291191 AL136295 AL832973 BC004159 BC010887 BC019326 CH471078 CR457263
GenPept AAD01193 AAH04159 AAH10887 AAH19326 BAA91690 BAF83880 CAG33544 CAH56339 EAW66089 EAW66090