Version 5.4
Homo sapiens Protein: AKR1C3
Summary
InnateDB Protein IDBP-813412.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKR1C3
Protein Name aldo-keto reductase family 1, member C3
Synonyms DD3; DDX; HA1753; HAKRB; HAKRe; hluPGFS; HSD17B5; PGFS;
Species Homo sapiens
Ensembl Protein ENSP00000474188
InnateDB Gene IDBG-47964 (AKR1C3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 5 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR020471 Aldo/keto reductase subgroup
IPR023210 NADP-dependent oxidoreductase domain
PFAM PF00248
PRINTS PR00069
PIRSF PIRSF000097
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL S4R3D5
UniProt Splice Variant
Entrez Gene 8644
UniGene
RefSeq
HUGO HGNC:386
OMIM 603966
CCDS
HPRD
IMGT
EMBL AL391427
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca