InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SETD1B

Summary

InnateDB Protein

IDBP-813615.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SETD1B

Protein Name

SET domain containing 1B

Synonyms

KMT2G; Set1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000481531

InnateDB Gene

IDBG-62002 (SETD1B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0042800	histone methyltransferase activity (H3-K4 specific)

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0051568	histone H3-K4 methylation

Cellular Component

GO:0005634	nucleus
GO:0005694	chromosome
GO:0016607	nuclear speck
GO:0035097	histone methyltransferase complex
GO:0048188	Set1C/COMPASS complex

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain
IPR001214 SET domain
IPR003616 Post-SET domain
IPR024657 COMPASS complex Set1 subunit, N-SET domain

PFAM

PF00076
PF00856
PF11764

PRINTS

PIRSF

SMART

SM00360
SM00317
SM00508

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

23067

UniGene

RefSeq

HUGO

HGNC:29187

OMIM

611055

CCDS

HPRD

IMGT

EMBL

AB028999 AC079360 AC084018 JF813787

GenPept

AEG67286 BAA83028