InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NXT2

Summary

InnateDB Protein

IDBP-82181.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NXT2

Protein Name

nuclear transport factor 2-like export factor 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000361179

InnateDB Gene

IDBG-82177 (NXT2)

Protein Structure

UniProt Annotation

Function

Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export.

Subcellular Localization

Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006810	transport
GO:0015031	protein transport
GO:0051028	mRNA transport

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR002075 Nuclear transport factor 2
IPR018222 Nuclear transport factor 2, eukaryote

PFAM

PF02136

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NPJ8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

55916

UniGene

Hs.599904

RefSeq

HUGO

HGNC:18151

OMIM

300320

CCDS

CCDS56606

HPRD

02264

IMGT

EMBL

AF201942 AF212223 AF246127 AJ277591 AJ278323 AK023289 AL031387 BC014888 BC120984 BC120985 CH471120

GenPept

AAF78034 AAF86878 AAF87325 AAI20985 AAI20986 BAB14511 CAB96371 CAC01129 CAI42967 CAI42968 CAI42969 EAX02677 EAX02678 EAX02680