Version 5.4
Homo sapiens Gene: NXT2
Summary
InnateDB Gene IDBG-82177.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NXT2
Gene Name nuclear transport factor 2-like export factor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101888
Encoded Proteins
IDBP-82179
nuclear transport factor 2-like export factor 2
IDBP-82181
nuclear transport factor 2-like export factor 2
IDBP-82183
nuclear transport factor 2-like export factor 2
IDBP-82185
nuclear transport factor 2-like export factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:109535781-109544690
Strand Forward strand
Band q23
Transcripts
ENST00000218004 ENSP00000218004
ENST00000372107 ENSP00000361179
ENST00000372106 ENSP00000361178
ENST00000372103 ENSP00000361175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042271
View Gene Order
ENSBTAG00000020739
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9NPJ8
TrEMBL
UniProt Splice Variant
Entrez Gene 55916
UniGene Hs.25010 Hs.599904
RefSeq NM_001242617 NM_001242618 NM_018698
HUGO HGNC:18151
OMIM 300320
CCDS CCDS14546 CCDS56605 CCDS56606
HPRD
IMGT
EMBL AF201942 AF212223 AF246127 AJ277591 AJ278323 AK023289 AL031387 BC014888 BC120984 BC120985 CH471120
GenPept AAF78034 AAF86878 AAF87325 AAI20985 AAI20986 BAB14511 CAB96371 CAC01129 CAI42967 CAI42968 CAI42969 EAX02677 EAX02678 EAX02680
RNA Seq Atlas 55916

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca